Lei Wang

I am an Associate Research Professor at Central China Normal University and a member of Professor Guangfu Yang’s group. I received my PhD in Bioinformatics Engineering from Huazhong University of Science and Technology in December 2023, and completed postdoctoral research at its School of Computer Science and Technology from 2024 to July 2026 with iSyslab. I work at the intersection of artificial intelligence and bioinformatics, focusing on protein language models, sequence and structure analysis, RNA structure prediction, peptide therapeutics, and bioinformatics tools.

Publications Get in touch

Google Scholar ORCID GitHub

news

More news

2026.10.06

Publication

RAFA available online in Bioinformatics

2026.08.14

Publication

ProtFormer-Site published in Interdisciplinary Sciences

2026.01.27

Publication

LocPred-Prok published in Journal of Molecular Biology

selected publications

RAFA: RNA all-atom structure reconstruction from sparse anchor coordinates

Lei Wang, and Zilu Zeng

Bioinformatics 2026

Code
Interdiscip. Sci.

ProtFormer-Site: Ultra-fast and Accurate Prediction of Protein-Protein Interaction Sites with Protein Language Model

Lei Wang, Shali Dong, Han Zhang, and 4 more authors

Interdisciplinary Sciences: Computational Life Sciences 2026

Code
J. Mol. Biol.

LocPred-Prok: Prokaryotic protein subcellular localization prediction with a dual-branch architecture and protein language model

Zilu Zeng, and Lei Wang

Journal of Molecular Biology 2026

Code
arXiv

A Comprehensive Review of Protein Language Models

Lei Wang, Xudong Li, Han Zhang, and 4 more authors

arXiv preprint arXiv:2502.06881 2025

Website
BIBM

ProtSSSD: A Novel Approach for Intrinsically Disordered Protein Region Prediction Using Protein Language Model

Lei Wang, Zilu Zeng, Yan Wang, and 1 more author

In IEEE International Conference on Bioinformatics and Biomedicine 2025

Code
CSBJ

DeepNeuropePred: A robust and universal tool to predict cleavage sites from neuropeptide precursors by protein language model

Lei Wang, Zilu Zeng, Zhidong Xue, and 1 more author

Computational and Structural Biotechnology Journal 2024

Code
Cell Rep. Phys. Sci.

Deciphering the protein landscape with ProtFlash, a lightweight language model

Lei Wang, Hui Zhang, Wei Xu, and 2 more authors

Cell Reports Physical Science 2023

Code
NeuroPred-PLM: an interpretable and robust model for neuropeptide prediction by protein language model

Lei Wang, Chen Huang, Mingxia Wang, and 2 more authors

Briefings in Bioinformatics 2023

Code
CSBJ

Improving the topology prediction of α-helical transmembrane proteins with deep transfer learning

Lei Wang, Haolin Zhong, Zhidong Xue, and 1 more author

Computational and Structural Biotechnology Journal 2022

Code