Our paper, RAFA: RNA all-atom structure reconstruction from sparse anchor coordinates, is now available online as an accepted manuscript in Bioinformatics.
RAFA is a C++ command-line tool for reconstructing RNA all-atom structures from sparse or partial anchor coordinates. It retrieves experimentally observed fragments and combines them through anchor fitting and weighted consensus, providing a practical route from coarse structural information to atomic models.
中文简介
论文 RAFA: RNA all-atom structure reconstruction from sparse anchor coordinates 已以 accepted manuscript 形式在线发表于 Bioinformatics。
RAFA 是一款 C++ 命令行工具，可根据稀疏或不完整的锚点坐标重建 RNA 全原子结构。该方法检索实验观测到的 RNA 片段，并通过锚点拟合与加权共识生成原子模型，为从粗粒度结构信息获得全原子模型提供了实用方案。